Unrecognized human immunodeficiency virus infection and risk factors among elderly medical patients at the Korle Bu teaching hospital, Accra, Ghana
Identifieur interne : 000118 ( Main/Exploration ); précédent : 000117; suivant : 000119Unrecognized human immunodeficiency virus infection and risk factors among elderly medical patients at the Korle Bu teaching hospital, Accra, Ghana
Auteurs : Andrew A. Adjei [Ghana] ; Seth Agyemang [Ghana] ; Francis D. Krampa [Ghana] ; Mubarak Abdul-Rahman [Ghana] ; Francis Ofei [Ghana] ; Margaret Lartey [Ghana] ; Theophilus K. Adiku [Ghana] ; Richard K. Gyasi [Ghana] ; Yao Tettey [Ghana]Source :
- Tropical Diseases, Travel Medicine and Vaccines [ 2055-0936 ] ; 2016.
Abstract
The human immunodeficiency virus (HIV) infection usually infects persons in the reproductive age group (15–49 years), but elderly people are also susceptible. Many people in sub-Saharan Africa including Ghana believe that elderly people are not at risk for HIV. Despite numerous reports of the high prevalence of HIV infection among the elderly worldwide, there are no from Ghana. This work determined the sero-prevalence of HIV infection and risk factors for its transmission among 1,100 hospitalized elderly people at the Korle Bu Teaching Hospital (KBTH), Accra, Ghana.
Subjects voluntarily completed a risk-factor questionnaire and provided a blood specimen for HIV testing.
Of the study participants, 440 were male (mean age: 64 ± 10.55 years), and 660 were female (mean age: 63 ± 9.51 years). The overall HIV-1 sero-prevalence among the subjects was 4.18 % (
The results suggest high prevalence of HIV-1 among hospitalized elderly people at KBTH, recommending the need to include the elderly in HIV/AIDS testing, prevention, and control programmes.
Trial registration number: MS-Et/M.9 - p4.10/2012–2013. Registered: 10th April, 2013.
Url:
DOI: 10.1186/s40794-016-0034-9
PubMed: 28883962
PubMed Central: 5530923
Affiliations:
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Adiku</name><affiliation wicri:level="1"><nlm:aff id="Aff3"><institution-wrap><institution-id institution-id-type="GRID">grid.8652.9</institution-id><institution-id institution-id-type="ISNI">0000000419371485</institution-id><institution>Department of Microbiology, School of Biomedical and Allied Health Sciences, College of Health Sciences,</institution><institution>University of Ghana,</institution></institution-wrap>Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Accra</wicri:regionArea></affiliation></author><author><name sortKey="Gyasi, Richard K" sort="Gyasi, Richard K" uniqKey="Gyasi R" first="Richard K." last="Gyasi">Richard K. Gyasi</name><affiliation wicri:level="1"><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="GRID">grid.8652.9</institution-id><institution-id institution-id-type="ISNI">0000000419371485</institution-id><institution>Department of Pathology, School of Biomedical and Allied Health Sciences, College of Health Sciences,</institution><institution>University of Ghana,</institution></institution-wrap>Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Accra</wicri:regionArea></affiliation></author><author><name sortKey="Tettey, Yao" sort="Tettey, Yao" uniqKey="Tettey Y" first="Yao" last="Tettey">Yao Tettey</name><affiliation wicri:level="1"><nlm:aff id="Aff4"><institution-wrap><institution-id institution-id-type="GRID">grid.8652.9</institution-id><institution-id institution-id-type="ISNI">0000000419371485</institution-id><institution>Department of Pathology, School of Biomedical and Allied Health Sciences, College of Health Sciences,</institution><institution>University of Ghana,</institution></institution-wrap>Accra, Ghana</nlm:aff><country xml:lang="fr">Ghana</country><wicri:regionArea>Accra</wicri:regionArea></affiliation></author></analytic><series><title level="j">Tropical Diseases, Travel Medicine and Vaccines</title><idno type="eISSN">2055-0936</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p id="Par1">The human immunodeficiency virus (HIV) infection usually infects persons in the reproductive age group (15–49 years), but elderly people are also susceptible. Many people in sub-Saharan Africa including Ghana believe that elderly people are not at risk for HIV. Despite numerous reports of the high prevalence of HIV infection among the elderly worldwide, there are no from Ghana. This work determined the sero-prevalence of HIV infection and risk factors for its transmission among 1,100 hospitalized elderly people at the Korle Bu Teaching Hospital (KBTH), Accra, Ghana.</p></sec><sec><title>Methods</title><p id="Par2">Subjects voluntarily completed a risk-factor questionnaire and provided a blood specimen for HIV testing.</p></sec><sec><title>Results</title><p id="Par3">Of the study participants, 440 were male (mean age: 64 ± 10.55 years), and 660 were female (mean age: 63 ± 9.51 years). The overall HIV-1 sero-prevalence among the subjects was 4.18 % (<italic>n</italic> = 46). On multivariate analysis, there was no statistical significance between the socio-demographics or risk factors and the HIV status of the participants.</p></sec><sec><title>Conclusion</title><p id="Par4">The results suggest high prevalence of HIV-1 among hospitalized elderly people at KBTH, recommending the need to include the elderly in HIV/AIDS testing, prevention, and control programmes.</p></sec><sec><title>Trial registration</title><p id="Par5">Trial registration number: MS-Et/M.9 - p4.10/2012–2013. 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Pallangyo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kassau, A" uniqKey="Kassau A">A Kassau</name></author><author><name sortKey="Mekonnen, A" uniqKey="Mekonnen A">A Mekonnen</name></author><author><name sortKey="Bekele, A" uniqKey="Bekele A">A Bekele</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Nyigo, V" uniqKey="Nyigo V">V Nyigo</name></author><author><name sortKey="Kilale, A" uniqKey="Kilale A">A Kilale</name></author><author><name sortKey="Kilima, S" uniqKey="Kilima S">S Kilima</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Anderson, A" uniqKey="Anderson A">A Anderson</name></author><author><name sortKey="Qingsi, Z" uniqKey="Qingsi Z">Z Qingsi</name></author><author><name sortKey="Hua, X" uniqKey="Hua X">X Hua</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lurie, M" uniqKey="Lurie M">M Lurie</name></author><author><name sortKey="William, B" uniqKey="William B">B William</name></author><author><name sortKey="Suma, K" uniqKey="Suma K">K Suma</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Foss, Am" uniqKey="Foss A">AM Foss</name></author><author><name sortKey="Watts, Ch" uniqKey="Watts C">CH Watts</name></author><author><name sortKey="Vickerman, P" uniqKey="Vickerman P">P Vickerman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Holmes, Kk" uniqKey="Holmes K">KK Holmes</name></author><author><name sortKey="Levine, R" uniqKey="Levine R">R Levine</name></author><author><name sortKey="Weaver, M" uniqKey="Weaver M">M Weaver</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Ghana</li></country><region><li>Région du Grand Accra</li></region><settlement><li>Accra</li><li>Legon (Ghana)</li></settlement><orgName><li>Université du Ghana</li></orgName></list><tree><country name="Ghana"><region name="Région du Grand Accra"><name sortKey="Adjei, Andrew A" sort="Adjei, Andrew A" uniqKey="Adjei A" first="Andrew A." last="Adjei">Andrew A. Adjei</name></region><name sortKey="Abdul Rahman, Mubarak" sort="Abdul Rahman, Mubarak" uniqKey="Abdul Rahman M" first="Mubarak" last="Abdul-Rahman">Mubarak Abdul-Rahman</name><name sortKey="Adiku, Theophilus K" sort="Adiku, Theophilus K" uniqKey="Adiku T" first="Theophilus K." last="Adiku">Theophilus K. Adiku</name><name sortKey="Adjei, Andrew A" sort="Adjei, Andrew A" uniqKey="Adjei A" first="Andrew A." last="Adjei">Andrew A. Adjei</name><name sortKey="Agyemang, Seth" sort="Agyemang, Seth" uniqKey="Agyemang S" first="Seth" last="Agyemang">Seth Agyemang</name><name sortKey="Gyasi, Richard K" sort="Gyasi, Richard K" uniqKey="Gyasi R" first="Richard K." last="Gyasi">Richard K. Gyasi</name><name sortKey="Krampa, Francis D" sort="Krampa, Francis D" uniqKey="Krampa F" first="Francis D." last="Krampa">Francis D. Krampa</name><name sortKey="Lartey, Margaret" sort="Lartey, Margaret" uniqKey="Lartey M" first="Margaret" last="Lartey">Margaret Lartey</name><name sortKey="Ofei, Francis" sort="Ofei, Francis" uniqKey="Ofei F" first="Francis" last="Ofei">Francis Ofei</name><name sortKey="Tettey, Yao" sort="Tettey, Yao" uniqKey="Tettey Y" first="Yao" last="Tettey">Yao Tettey</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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